Thalamic cholinergic innervation and postural sensory integration function in Parkinson’s disease
نویسندگان
چکیده
منابع مشابه
Distinct forms of cholinergic modulation in parallel thalamic sensory pathways.
Mammalian thalamus is a critical site where early perception of sensorimotor signals is dynamically regulated by acetylcholine in a behavioral state-dependent manner. In this study, we examined how synaptic transmission is modulated by acetylcholine in auditory thalamus where sensory relay neurons form parallel lemniscal and nonlemniscal pathways. The former mediates tonotopic relay of acoustic...
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The theory and practice of sensory integration were developed in the late 1960s by an occupational therapist and psychologist, Dr. A. Jean Ayres [1]. Also, known as sensory processing, it is “the neurological process that organizes sensation from one’s own body and from the environment and makes it possible to use the body effectively within the environment” [1].
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Previous studies of the development of cholinergic sympathetic innervation of sweat glands in rat footpads suggested that these terminals initially exhibit noradrenergic properties which are lost as the glands and their innervation mature. We have treated neonatal and adult rats with 6-hydroxydopamine (6-OHDA), a toxic congener of norepinephrine, and compared its effects on the cholinergic symp...
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Low threshold Ca2+ currents mediated by T-type channels underlie burst spike activities of relay neurons in the thalamus. We have previously reported that knock-out mice for T-type channels show an enhanced nociceptive response to visceral pain, accompanied by an increase in tonic spikes in the absence of burst spikes in thalamic relay neurons. These results raised a possibility that T-type cha...
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(Received for publication, July 21, 1952) Many histological studies1),2),3) on the innervation of mammalian tongues have been reported and praiseworthy results achieved histherto, but much seems yet left unexplored, and in particular, many questions are still waiting solution in connection with dog tongue. Recently, much licht has been thrown on the subject of innervation of human tongue by the...
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ژورنال
عنوان ژورنال: Brain
سال: 2013
ISSN: 1460-2156,0006-8950
DOI: 10.1093/brain/awt247